Blogworthy Articles in NEJM

The most recent (3/25/06) issue of the New England Journal of Medicine contains several items that deserve a mention here at Corpus Callosum.  It is worth noting that there are three items related to psychopharmacology; this degree of attention is unusual in a general medical journal.  All require a subscription for the full text.

There are two papers that report on results from the STAR*D (Sequenced Treatment Alternatives to Relieve Depression) project.  One study shows what happens when patients are switched from one antidepressant that is not working for them, to a different one.  The other shows what happens when a second drug is added to the first one.   The third paper discusses what is known about the cardiovascular risk of stimulant medications used to treat ADHD.  Continue reading here.